影响慢性肾病 model projects up to 16.到2032年，将有8个国家5%的人口患有慢性肾病
A new modelling analysis by 澳门在线赌城娱乐, 影响慢性肾病, forecasts up to 16.到2032年，8个国家5%的人口将患有慢性肾脏疾病(慢性肾病), including a rise of up to 59.3%为晚期.1 Presented at the 2024 ISN World Congress of Nephrology (WCN’24) in Buenos Aires, 这项研究强调了一个紧迫和日益严重的全球健康危机，具有深远的经济和环境影响.1 影响慢性肾病 is the first study to examine and forecast the vast, 在10年的时间跨度内对8个国家(包括美国)慢性肾病的多维影响进行了研究, 巴西, 英国, 西班牙, 德国, 荷兰, 中国, 和澳大利亚.1
该研究估计，到2032年，这些国家将有近1.25亿人患有晚期慢性肾病, marking a 25% increase since 2022 when the model began.1 The 经济 toll of renal replacement therapy, including dialysis and transplant, is anticipated to reach approximately $186 billion, and dialysis requirements are expected to surge by over 75%, 显著增加了医疗保健行业的碳足迹——相当于增加了约17个碳足迹.3 million cars' worth of CO2 emissions.1
路德浮标, 执行副总裁, 澳门第一赌城在线娱乐 Business Unit, 澳门在线赌城娱乐, highlights: “Our modelling emphasises the enormous impact 慢性肾病 could have on patients, economies and the environment. But this future is not inevitable. 在澳门在线赌城娱乐, 澳门第一赌城在线娱乐致力于与全球决策者合作，减少终末期慢性肾病的全球影响，推动早期诊断和治疗，以减缓或停止疾病进展.”
影响慢性肾病研究是澳门在线赌城娱乐慢性肾病加速变化(ACT)计划的一部分, aiming to improve understanding and outcomes of 慢性肾病 worldwide. Through the 治疗慢性肾病 programme, 澳门在线赌城娱乐, alongside the 全球 Patient Alliance for Kidney Health (GloPAKH), 已经推出了Make the Change for Kidney Health的竞选. This initiative seeks to elevate 慢性肾病 on the global policy agenda, 倡导全面和有效的疾病管理战略，以应对这一不断升级的健康挑战.
笔记
慢性肾病
慢性肾病是一种严重的疾病, 以肾功能下降为特征的进行性疾病(表现为eGFR降低或肾损害标志物), 或两个, for at least three months).2 Nearly 850 million people worldwide are affected by 慢性肾病,3 with the majority undiagnosed.2 The most common causes of 慢性肾病 are diabetes, hypertension and glomerulonephritis.4 慢性肾病与显著的患者发病率和心血管(CV)事件风险增加相关, such as heart failure (HF), which drives premature death.5 以最严重的形式, 也就是肾衰竭, 肾损害和肾功能恶化已发展到需要透析或肾移植的程度.6 大多数慢性肾病患者在达到肾衰竭之前会死于CV原因.7
影响慢性肾病
影响慢性肾病是一项创新研究，它结合了一个复杂的模拟模型，揭示了慢性肾脏疾病(慢性肾病)在临床中的广泛影响的整体预测, 经济, 社会, and environmental dimensions.1 This landmark analysis delivers the first-ever, 10-year outlook on the impact of 慢性肾病, providing insight for the United States, 巴西, 英国, 西班牙, 德国, 荷兰, 中国, 和澳大利亚.1 Emphasizing the critical importance of early 慢性肾病 detection and treatment, 该研究提供了旨在实质性减轻该疾病多方面负担的战略见解.1
治疗慢性肾病
治疗慢性肾病是澳门在线赌城娱乐(澳门在线赌城娱乐)的一个项目，旨在通过合作伙伴关系改变肾脏健康，旨在到2025年将进展为肾衰竭的患者比例降低20%. 为了实现这一目标, 该方案支持旨在提高对慢性肾病负担及其后果的认识的举措, 扩大早期发现并推动治疗优化，以改善患者预后. To further support people at risk of 慢性肾病, we also look to achieve sustainable change through health policy reforms.
We want to provide patients, 医疗保健提供者(HCPs)和决策者提供必要的信息来推动变革. As a part of our broader contribution to building knowledge around 慢性肾病 we continue to generate evidence to help advance clinical practice: DISCOVER-慢性肾病 shows a lack of urine albumin-creatinine ratio (UACR) testing and ad在这里nce to Kidney Disease Improving 全球 Outcomes (KDIGO) guidelines; REVEAL-慢性肾病 shows the extent of the gaps in early detection of 慢性肾病 and the clear benefits of diagnosing early; INSIDE-慢性肾病 shows the unsustainable future burden of 慢性肾病 and potential benefits to the healthcare system of improved management; PACE-慢性肾病 shows 慢性肾病 is associated with a poorer quality of life not only for patients but also their carers; and 影响慢性肾病 provides modelling of the future 慢性肾病 burden for public health policy planning, including 社会 and environmental impact.
The World Congress of Nephrology (WCN)
The World Congress of Nephrology (WCN) is the annual scientific, 教育, and networking meeting of the International Society of Nephrology (ISN).8 美国肾脏学会是一个全球性的专业协会，自1960年以来一直致力于通过教育促进全球肾脏健康, 奖助金, 研究, 和宣传.8
澳门在线赌城娱乐在crvrm
心血管, 肾 and Metabolism (CVRM), part of 澳门第一赌城在线娱乐, 是澳门在线赌城娱乐的主要疾病领域之一，也是公司的关键增长动力. 通过遵循科学来更清楚地了解心脏之间的潜在联系, 肾脏, 肝脏和胰腺, 澳门在线赌城娱乐正在投资一系列药物，通过减缓或阻止疾病进展来保护器官, and ultimately paving the way towards regenerative therapies. The Company’s ambition is to improve and save the lives of millions of people, 通过更好地理解crvrm疾病之间的相互联系，并针对驱动它们的机制, 所以澳门第一赌城在线娱乐可以检测, diagnose and treat people earlier and more effectively.
澳门在线赌城娱乐
澳门在线赌城娱乐 (LSE/STO/Nasdaq: AZN) is a global, science-led biopharmaceutical company that focuses on the discovery, 发展, and commercialisation of prescription medicines in 肿瘤学, 罕见疾病, 和澳门第一赌城在线娱乐, 包括心血管, 肾 & Metabolism, and 呼吸 & 免疫学. 总部设在剑桥, UK, 澳门在线赌城娱乐在100多个国家开展业务，其创新药物被全球数百万患者使用. 请访问 澳门在线赌城娱乐.com and follow the Company on social media @澳门在线赌城娱乐
联系
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参考文献
1. 饶宁，等. 八个国家慢性肾脏疾病的多维负担:来自影响慢性肾病研究的见解. Presented at: WCN 2024, 13-16 April 2024, Buenos Aires, Argentina.
2. Bikbov B，等. 全球, 区域, and national burden of chronic 肾脏 disease, 1990–2017: a systematic analysis for the 全球 Burden of Disease Study 2017. 《澳门在线赌城娱乐》. 2020;395(10225):709-733.
3. Jager KJ，等. 一个倡导和沟通的数字——全世界有超过8.5亿人患有肾脏疾病. 肾盘移植. 2019;34(11):1803-1805.
4. National Kidney Foundation [Internet]. Chronic Kidney Disease (慢性肾病); [cited 2024 March 25]. Available from: http://www.肾脏.org/atoz/content/about-chronic-肾脏-disease.
5. Centers for Disease Control and Prevention (CDC) [Internet]. Chronic Kidney Disease: Common - Serious - Costly; [cited 2024 March 25]. Available from: http://www.疾病预防控制中心.gov/肾脏disease/prevention-risk/慢性肾病-common-serious-costly.html.
6. Centers for Disease Control and Prevention (CDC) [Internet]. Chronic 肾脏 disease in the United States; 2021 [cited 2024 March 25]. Available from: http://www.疾病预防控制中心.gov/肾脏disease/pdf/Chronic-Kidney-Disease-in-the-US-2021-h.pdf.
7. Briasoulis A等. Chronic 肾脏 disease as a coronary artery disease risk equivalent. 现任心脏病代表. 2013;15(3):340.
8. WCS(互联网). 国际肾脏病学大会(WCN’24)摘要禁运政策[引自2024年3月25日]. Available from: http://www.theisn.org/wcn/wp-content/uploads/sites/6/2023/06/WCN24-Abstract-Embargo-Policy.pdf.
Veeva ID: Z4-63620
Date of Preparation: April 2024
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